5-MTHF Extra Strength | Active Folate with Quatrefolic®

5-MTHF Extra Strength | Active Folate with Quatrefolic®

Support methylation, cardiovascular wellness, and cellular metabolism with RetzlerRx® 5-MTHF Extra Strength, a physician-formulated active folate supplement designed to provide the most biologically available form of vitamin B9.* This advanced formula uses Quatrefolic®, a highly bioavailable form of 5-methyltetrahydrofolate (5-MTHF) designed to support efficient folate utilization and cellular health.*

5-MTHF is the metabolically active form of folate used by the body in critical biochemical pathways including DNA synthesis, methylation, neurotransmitter production, and cardiovascular metabolism.* Unlike standard folic acid, which must be converted through multiple enzymatic steps, active folate provides the form the body can directly utilize.*

RetzlerRx® 5-MTHF Extra Strength is especially beneficial for individuals who may have difficulty converting folic acid efficiently, including those with MTHFR gene variations or those seeking advanced nutritional support for cellular and metabolic health.*

Key Benefits

• Active Folate with Quatrefolic® – Provides highly bioavailable methylfolate for efficient absorption and utilization.*
• Methylation Support – Supports critical methylation pathways involved in DNA synthesis and cellular metabolism.*
• Cardiovascular Support – Helps support healthy homocysteine metabolism and cardiovascular wellness.*
• Energy & Cognitive Support – Supports energy metabolism, neurotransmitter production, and mental clarity.*
• MTHFR-Friendly Formula – Ideal for individuals seeking active folate rather than synthetic folic acid.*
• Doctor Formulated – Developed using principles of functional and longevity medicine.
• Clean Formula – Vegan, gluten-free, and non-GMO.

Who May Benefit

• Individuals seeking methylation support
• People with MTHFR gene variants
• Those interested in cardiovascular wellness support
• Individuals seeking energy and neurological support
• People looking for bioactive folate supplementation

Why RetzlerRx®

RetzlerRx® supplements are developed using practitioner-grade standards and clinically relevant formulations. These products reflect the philosophy of HormoneSynergy® Longevity Medicine, where targeted nutrition, advanced diagnostics, and evidence-based preventive longevity medicine support long-term metabolic and neurological health.

• Physician formulated
• Practitioner-grade quality
• Clinically selected ingredients
• Non-GMO and gluten-free
• No unnecessary fillers

Suggested Use

Take as directed on the product label or as directed by your healthcare provider.

Frequently Asked Questions

What is 5-MTHF?

5-MTHF (5-methyltetrahydrofolate) is the active, bioavailable form of folate used directly by the body in methylation and cellular metabolism.*

What is Quatrefolic®?

Quatrefolic® is a patented form of methylfolate designed for enhanced stability, absorption, and biological activity.*

Why choose active folate instead of folic acid?

Active folate bypasses the enzymatic conversion steps required for folic acid, making it easier for the body to utilize in key biochemical pathways.*

Who may benefit from 5-MTHF supplementation?

Individuals seeking support for methylation, cardiovascular health, homocysteine metabolism, and neurological wellness may benefit from active folate supplementation.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

HormoneSynergy® Longevity Medicine
Portland • Lake Oswego • Oregon
Evidence-Based Preventive Longevity Medicine